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ADC Therapeutics
ADC Therapeutics
(ADCT)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Zynlonta
Loncastuximab tesirine
2021-04-23
Large b-cell lymphoma diffuse
,
B-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Loncastuximab tesirine
leukemia
,
lymphoid leukemia
,
b-cell chronic lymphocytic leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
burkitt lymphoma
,
central nervous system neoplasms
,
follicular lymphoma
,
mantle-cell lymphoma
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
recurrence
,
lymphoma
,
b-cell lymphoma
,
large b-cell lymphoma diffuse
,
non-hodgkin lymphoma
,
hodgkin disease
Epratuzumab
leukemia
,
lymphoid leukemia
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
philadelphia chromosome
,
recurrence
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
aggression
,
lymphoma
,
systemic lupus erythematosus
,
non-hodgkin lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
mantle-cell lymphoma
,
t-cell lymphoma peripheral
,
t-cell lymphoma cutaneous
Calcium dobesilate
multiple myeloma
,
plasma cell neoplasms
Bevifimod
alzheimer disease
,
myelodysplastic syndromes
,
liver diseases
,
hepatic insufficiency
,
cognitive dysfunction
,
precursor cell lymphoblastic leukemia-lymphoma
,
maximum tolerated dose
,
antineoplastic protocols
,
pharmacokinetics
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
covid-19
,
aplastic anemia
,
paraproteinemias
,
monoclonal gammopathy of undetermined significance
,
lymphocytosis
,
laboratory infection
,
myeloid leukemia acute
,
castration-resistant prostatic neoplasms
,
myeloid leukemia
,
neoplasms
,
hiv infections
,
acquired immunodeficiency syndrome
,
hematologic neoplasms
,
hiv
,
immunologic deficiency syndromes
,
syndrome
,
hypergammaglobulinemia
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
prostatic neoplasms
,
neoplasm metastasis
,
multiple myeloma
,
plasma cell neoplasms
,
colorectal neoplasms
,
colonic neoplasms
,
colonic diseases
,
virus diseases
,
sexually transmitted diseases
,
retroviridae infections
,
viral sexually transmitted diseases
,
b-cell lymphoma marginal zone
,
burkitt lymphoma
,
tuberculosis
,
pulmonary tuberculosis
,
healthy volunteers/patients
,
non-small-cell lung carcinoma
,
b-cell lymphoma
,
large b-cell lymphoma diffuse
,
non-hodgkin lymphoma
,
follicular lymphoma
,
lung neoplasms
,
graft vs host disease
,
bronchiolitis obliterans syndrome
,
renal insufficiency
,
respiratory syncytial viruses
,
psoriasis
,
ebola hemorrhagic fever
,
cerebrospinal fluid leak
,
hemorrhage
,
soft tissue injuries
,
respiratory tract diseases
,
kidney transplantation
,
prolymphocytic leukemia t-cell
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
leukemia
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
type 2 diabetes mellitus
,
diabetes mellitus
,
obesity
,
atrial fibrillation
CAMIDANLUMAB
renal cell carcinoma
,
carcinoma
,
colorectal neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
urinary bladder neoplasms
,
fallopian tube neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
lymphoma
,
hodgkin disease
,
myelodysplastic syndromes
,
neoplasms
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
preleukemia
CAMIDANLUMAB TESIRINE
non-small-cell lung carcinoma
,
urinary bladder neoplasms
,
renal cell carcinoma
,
carcinoma
,
colorectal neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
fallopian tube neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
breast neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
lymphoma
,
hodgkin disease
,
myelodysplastic syndromes
,
neoplasms
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
preleukemia
Loncastuximab
leukemia
,
lymphoid leukemia
,
b-cell chronic lymphocytic leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
burkitt lymphoma
,
central nervous system neoplasms
,
follicular lymphoma
,
mantle-cell lymphoma
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
recurrence
,
lymphoma
,
b-cell lymphoma
,
large b-cell lymphoma diffuse
,
non-hodgkin lymphoma
,
hodgkin disease
Nepidermin
chronic obstructive pulmonary disease
,
lung diseases
,
obstructive lung diseases
,
healthy volunteers/patients
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
recurrence
,
triple negative breast neoplasms
,
kidney neoplasms
,
fallopian tube neoplasms
,
carcinoma
,
prostatic neoplasms
,
neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
lymphoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
renal cell carcinoma
,
colorectal neoplasms
,
breast neoplasms
,
non-hodgkin lymphoma
,
hypertension
,
essential hypertension
,
castration-resistant prostatic neoplasms
,
melanoma
,
b-cell lymphoma
,
macular edema
,
edema
,
erectile dysfunction
,
large b-cell lymphoma diffuse
,
macular degeneration
,
infections
,
communicable diseases
,
trichuriasis
,
hookworm infections
,
ancylostomiasis
,
stroke
,
embolism
,
embolic stroke
,
pharyngitis
,
common cold
,
low back pain
,
back pain
,
acute coronary syndrome
,
syndrome
,
hypersensitivity
,
venous thromboembolism
,
thromboembolism
,
gastrointestinal stromal tumors
,
atrial fibrillation
,
glioblastoma
,
acne vulgaris
,
dysmenorrhea
,
pneumonia
,
bacterial pneumonia
,
neoplasm metastasis
,
thyroid neoplasms
,
thyroid diseases
,
retinal diseases
,
wet macular degeneration
,
retinal degeneration
,
eye diseases
,
heart failure
,
exanthema
Odronextamab
b-cell chronic lymphocytic leukemia
,
leukemia
,
reactive arthritis
,
lymphoid leukemia
,
recurrence
,
lymphoma
,
b-cell lymphoma
,
non-hodgkin lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
aggression
,
hodgkin disease
,
b-cell lymphoma marginal zone
Palifosfamide
sarcoma
,
rhabdomyosarcoma
,
lymphoma
Microcrystalline cellulose
psoriasis
Globulin, immune
thoracic neoplasms
,
herpes zoster
,
small cell carcinoma
,
b-cell lymphoma marginal zone
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
endocrine gland neoplasms
,
glandular and epithelial neoplasms
,
breast diseases
,
bronchial neoplasms
,
lymphoma
,
colorectal neoplasms
,
pancreatic neoplasms
,
adenocarcinoma
,
renal cell carcinoma
,
ovarian neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
sarcoma
,
urinary bladder neoplasms
,
ovarian epithelial carcinoma
,
neoplasm metastasis
,
liver neoplasms
,
follicular lymphoma
,
glioblastoma
,
squamous cell neoplasms
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
uterine cervical neoplasms
,
non-hodgkin lymphoma
,
esophageal neoplasms
,
urologic neoplasms
,
prostatic neoplasms
,
pancreatic ductal carcinoma
,
lymphoid leukemia
,
transitional cell carcinoma
,
esophageal squamous cell carcinoma
,
hodgkin disease
,
cholangiocarcinoma
,
stomach neoplasms
,
castration-resistant prostatic neoplasms
,
kidney neoplasms
,
leukemia
,
colonic neoplasms
,
kidney diseases
,
uterine neoplasms
,
urethral neoplasms
,
ureteral neoplasms
,
pelvic neoplasms
,
brain neoplasms
,
gliosarcoma
,
neoplasms by histologic type
,
adenoviridae infections
,
serous cystadenocarcinoma
,
endometrioid carcinoma
,
oncogenes
,
hepatocellular carcinoma
,
osteosarcoma
,
invasive hydatidiform mole
,
cutaneous malignant melanoma
,
histiocytic sarcoma
,
follicular dendritic cell sarcoma
,
interdigitating dendritic cell sarcoma
,
hemangiosarcoma
,
chronic kidney failure
,
renal insufficiency
,
carcinosarcoma
,
mullerian mixed tumor
,
glioma
,
nervous system diseases
,
nerve tissue neoplasms
,
primitive neuroectodermal tumors
,
neuroepithelial neoplasms
,
neuroectodermal tumors
,
bile duct neoplasms
,
chordoma
,
clear cell adenocarcinoma
,
acinar cell carcinoma
,
mycoses
,
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
syndrome
,
b-cell chronic lymphocytic leukemia
,
non-muscle invasive bladder neoplasms
,
unknown primary neoplasms
,
immunoblastic lymphadenopathy
,
enteropathy-associated t-cell lymphoma
,
intestinal diseases
,
panniculitis
,
merkel cell carcinoma
,
mouth neoplasms
,
oropharyngeal neoplasms
,
nasopharyngeal neoplasms
,
laryngeal neoplasms
,
hypopharyngeal neoplasms
,
leiomyosarcoma
,
malignant fibrous histiocytoma
,
neuroendocrine tumors
,
microsatellite repeats
,
astrocytoma
,
multiple myeloma
,
plasma cell neoplasms
,
rectal neoplasms
,
hypersensitivity
,
gastrointestinal stromal tumors
,
biliary tract neoplasms
,
male breast neoplasms
,
adenosquamous carcinoma
,
uveal neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
carcinoma
,
melanoma
,
squamous cell carcinoma of head and neck
,
breast neoplasms
,
head and neck neoplasms
,
squamous cell carcinoma
,
triple negative breast neoplasms
,
recurrence
,
endometrial neoplasms
,
fallopian tube neoplasms
,
small cell lung carcinoma
,
clostridium infections
,
skin neoplasms
,
hepatitis
,
hepatitis a
,
malignant mesothelioma
,
mesothelioma
,
juvenile arthritis
,
crohn disease
,
hepatitis b
,
whooping cough
,
neoplasms
,
arthritis
,
infections
,
rheumatoid arthritis
,
communicable diseases
,
ulcerative colitis
,
colitis
,
ulcer
,
hiv infections
,
papillomavirus infections
,
immunologic deficiency syndromes
,
papilloma
,
pneumococcal infections
,
prostatic intraepithelial neoplasia
,
carcinoma in situ
,
hiv
,
acquired immunodeficiency syndrome
,
uterine cervical dysplasia
,
dengue
,
hepatitis c
,
coronavirus infections
,
human influenza
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
human papillomavirus recombinant vaccine quadrivalent types 6 11 16 18
,
agammaglobulinemia
,
common variable immunodeficiency
,
papillomaviridae
,
chronic renal insufficiency
,
flavivirus infections
,
fibrosis
,
inflammation
,
coinfection
,
hypertension
,
prediabetic state
,
hypercholesterolemia
,
cerebrovascular disorders
,
diabetes mellitus
,
coronary artery disease
,
peripheral arterial disease
,
overweight
,
healthy volunteers/patients
Potassium magnesium citrate (4:1:2)
respiratory aspiration
,
healthy volunteers/patients
Doxorubin
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
bone marrow transplantation
,
acute disease
Ibi301
sickle cell anemia
,
beta-thalassemia
,
thalassemia
,
hemoglobinopathies
,
mycoses
,
carcinoma
,
breast neoplasms
,
adenocarcinoma
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
aplastic anemia
,
aids-related lymphoma
,
recurrence
,
non-hodgkin lymphoma
,
b-cell lymphoma marginal zone
,
hodgkin disease
,
myeloid leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia chronic-phase
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia juvenile
,
myeloid leukemia accelerated phase
,
t-cell lymphoma
,
burkitt lymphoma
,
blast crisis
,
biphenotypic leukemia acute
,
aggression
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
reactive arthritis
,
multiple myeloma
,
plasma cell neoplasms
,
myelomonocytic leukemia acute
,
neoplasms
,
refractory anemia with excess of blasts
,
myeloproliferative disorders
,
hairy cell leukemia
,
composite lymphoma
,
lymphoproliferative disorders
,
clonal hematopoiesis
,
cytopenia
,
histiocytosis
,
langerhans-cell histiocytosis
,
myelodysplastic-myeloproliferative diseases
,
large-cell lymphoma anaplastic
,
blastic plasmacytoid dendritic cell neoplasm
,
pathologic complete response
,
central nervous system neoplasms
,
hematopoietic stem cell transplantation
,
hyperglycemia
,
phenylketonurias
,
prolymphocytic leukemia
,
hiv infections
,
plasmablastic lymphoma
,
large-cell lymphoma immunoblastic
,
primary effusion lymphoma
,
lymphoma
,
b-cell lymphoma
,
leukemia
,
large b-cell lymphoma diffuse
,
lymphoid leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
follicular lymphoma
,
mantle-cell lymphoma
,
b-cell chronic lymphocytic leukemia
,
philadelphia chromosome
,
myeloid leukemia acute
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
waldenstrom macroglobulinemia
,
acute disease
,
inflammation
,
residual neoplasm
,
anemia
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